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National

After Exhausting Sexual Activity! 25-Year-Old Man Experiences Full-Body Pain Peak; Doctors Diagnose Rare Disease

A 25-year-old man was diagnosed with postorgasmic illness syndrome (POIS), a rare condition causing severe full-body pain, weakness, and exhaustion lasting up to a week after sexual climax since age 17. Doctors found vitamin B3 supplements

After Exhausting Sexual Activity! 25-Year-Old Man Experiences Full-Body Pain Peak; Doctors Diagnose Rare Disease
23 May Khaosod

A 25-year-old man has endured a debilitating condition since age 17, where approximately one hour after sexual climax, his body enters a severe state of exhaustion accompanied by muscle and joint pain throughout his body, with weakness lasting up to a week. This condition has made him fearful of sexual intimacy for years, severely affecting his quality of life to the point where he initially believed it was a psychological issue and sought psychiatric treatment, though no underlying cause was found.

What happened to this man? The foreign health page "Tensia" published a rare case study of this 25-year-old, noting that since age 17, approximately one hour after each climax, he enters a severe collapse lasting up to a week, with full-body pain and extreme weakness to the point of being unable to stand. After thorough examination, doctors found that various hormone levels were normal and ruled out common physical diseases before diagnosing him with a rare condition called "Postorgasmic Illness Syndrome" or POIS.

What are the symptoms of this rare disease? The main symptoms of POIS include systemic inflammation following sexual climax, with patients potentially experiencing fever, chills, brain fog or slowed thinking, and severe exhaustion. Currently, medical professionals theorize that these symptoms may be related to the body's allergic reaction to components in seminal fluid, resulting in the release of inflammatory substances similar to an infection mechanism.

However, there is good news from clinical trials showing that taking 500 milligrams of Vitamin B3 daily for several consecutive months can significantly reduce inflammation and alleviate exhaustion symptoms. Although the exact mechanism is still being studied, this represents important hope for patients.

Fear of seeing a doctor may cause even more serious consequences Tensia also emphasizes that POIS patients face not only physical suffering but also significant psychological pressure. Many choose to suffer in silence because they feel embarrassed or don't realize this is an actual disease, affecting their relationships and daily life. Doctors warn that the number of actually diagnosed patients may be lower than reality, and those with similar symptoms should promptly seek evaluation from urological specialists to prevent this hidden condition from becoming a long-term burden on their lives.

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