Irregular Periods May Signal PMOS, Experts Warn
Women dismissing irregular periods, acne, and weight gain as normal may actually have PMOS, a common hormonal disorder affecting 6–13% of women globally that increases risks of diabetes, heart disease, and mental health issues if untreated.
Women experiencing irregular periods, persistent acne, easy weight gain, or unusual hair growth often dismiss these symptoms as normal hormonal fluctuations, when they may actually signal Polyendocrine Metabolic Ovarian Syndrome (PMOS)—a common endocrine disorder among reproductive-age women that can significantly affect health if left untreated. According to the World Health Organization, PMOS affects 6–13% of women globally, yet many remain undiagnosed because early symptoms are unclear or perceived as normal, delaying timely treatment. Research shows that women with PMOS face increased risks of insulin resistance, type 2 diabetes, high blood pressure, abnormal cholesterol, fatty liver disease, and mental health issues such as anxiety and depression, making early diagnosis and ongoing medical management critical for long-term health. Current treatment guidelines recommend personalized care tailored to each patient's symptoms, age, body mass index, fertility goals, and other risk factors—potentially involving lifestyle changes, nutrition, exercise, weight management, mental health support, and medication as needed. September is recognized annually as PMOS Awareness Month to promote education, build understanding, and encourage women to seek screening and early treatment under medical supervision. Enrique Calvo, General Manager and Head of Southeast Asia Region at Exeltis Thailand, noted that many women live unaware with PMOS symptoms, mistaking them for normal bodily changes, when early diagnosis enables proper health planning and improved long-term quality of life. Exeltis Thailand, a pharmaceutical specialist from Spain, supports medical education on women's health conditions and has developed innovations including a combined-hormone birth control pill designed to address the underlying causes of acne, oily skin, excessive hair, and irregular menstruation.